Category: Stem Cells Research

Vascular dementia (VD) is the second most common cause of dementia following Alzheimer’s disease (AD). The major symptoms of VD including memory loss, language deficits and impairment of executive functions. Its specific etiology and pathogenesis remain unknown. Currently, treatment options of VD are still limited. The therapeutic strategies aim to control the vascular risk factors…

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We aimed to investigate whether the mesenchymal stem cell-endothelial cell crosstalk enhances angiogenic factor expression via nuclear factor kappa B (NF-κB) dependent mechanisms.Human dermal microvascular endothelial cells (HDMECs) and stem cells from human exfoliated deciduous teeth (SHEDs) were co-cultured for 96 h, in the presence of NF-κB decoy oligodeoxynucleotides (ODN) or scramble (control). Vascular endothelial…

Read More “Crosstalk between Dental Pulp Stem Cells and Endothelial Cells Augments Angiogenic Factor Expression” »